Lymphotoxin-dependent elevated meningeal CXCL13:BAFF ratios drive gray matter injury

Ikbel Naouar, Andrei Pangan, Michelle Zuo, Syed Ali Raza, Kevin Champagne-Jorgensen, Jyot Patel, Angela Wang, Annie Pu, Lesley Ward, Jennifer S Y Ahn, Faizah N Sayeed, Jingwen Zhu, Elisabeth Pössnecker, Shoshana Spring, John G Sled, Bruno Cenni, Barbara Nuesslein-Hildesheim, Jeffrey L Browning, Anne-Katrin Pröbstel, Daniel S Reich, Jennifer L Gommerman, Valeria Ramaglia

Nature Immunology, Springer Science and Business Media LLC, 2026 Jan

Dynamic alterations of dural and bone marrow B cells in an animal model of progressive multiple sclerosis

Alexandra Florescu, Michelle Zuo, Angela A. Wang, K. Champagne-Jorgensen, Mohammed Ariyan Noor, L. Ward, Erwin van Puijenbroek, C. Klein, J. Gommerman

Journal of Experimental Medicine, vol. 222(12), 2025, pp. e20241255

Mining for disease-associated microbial metabolites in an age-dependent model of multiple sclerosis

A. Pu, N. Fettig, Alexandros Polyzois, Gary Chao, Ikbel Naouar, L. S. Hohman, Marissa A Fontaine, Michelle Zuo, K. Champagne-Jorgensen, Julia Copeland, Donny Chan, Katherine M Davis, Ruoqi Yu, S. Popple, Natalia A. Carranza García, D. Guttman, Kathy D McCoy, V. Ramaglia, F. Schroeder, J. Gommerman, L. Osborne

bioRxiv, 2025

Two of a kind, one with MS: Gut microbes tip the balance.

K. Champagne-Jorgensen, J. Gommerman

Science immunology, 2025

Ecological and Immune Pressures Shape Outcomes of Precision Phage Therapy in Advanced Cystic Fibrosis Lung Disease

T. Luong, L. Kharrat, K. Champagne-Jorgensen, J. Melendez, D. Pride, D. J. Conrad, D. Roach

medRxiv, 2025

Astrocytes ACLYmate to chronic neuroinflammation.

K. Champagne-Jorgensen, J. Gommerman

Trends in immunology, 2024

Immunogenicity of bacteriophages

Kevin Champagne-Jorgensen, Tiffany Luong, Taylor Darby, Dwayne R. Roach

Trends in Microbiology, 2023

The Role of the Microbiota-Gut-Brain Axis in Neurodevelopment and Mental Health in Childhood and Adolescence

Kevin Champagne-Jorgensen, Karen-Anne McVey Neufeld

Kathrin Cohen Kadosh, The Oxford Handbook of Developmental Cognitive Neuroscience, Oxford University Press, 2022

The effect of microbiota on behaviour

Kevin Champagne-Jorgensen, K. McVey Neufeld

Modern Trends in Psychiatry, Microbes and the Mind: The Impact of the Microbiome on Mental Health, Karger, 2021

Membrane vesicles of Lacticaseibacillus rhamnosus JB-1 contain immunomodulatory lipoteichoic acid and are endocytosed by intestinal epithelial cells

Kevin Champagne-Jorgensen, M. F. Mian, K. McVey Neufeld, A. Stanisz, J. Bienenstock

Scientific Reports, 2021

Bacterial membrane vesicles and phages in blood after consumption of Lacticaseibacillus rhamnosus JB-1

Kevin Champagne-Jorgensen, Tamina A Jose, A. Stanisz, M. F. Mian, Alexander P Hynes, J. Bienenstock

Gut Microbes, 2021

The vagus nerve is necessary for the rapid and widespread neuronal activation in the brain following oral administration of psychoactive bacteria

A. Bharwani, C. West, Kevin Champagne-Jorgensen, K. M. Neufeld, Joseph Ruberto, W. Kunze, J. Bienenstock, P. Forsythe

Neuropharmacology, 2020

An electroencephalographic examination of the autonomous sensory meridian response (ASMR)

B. Fredborg*, Kevin Champagne-Jorgensen*, A. S. Desroches, Stephen D. Smith

Consciousness and Cognition, 2020

Microvesicles from Lactobacillus reuteri (DSM-17938) completely reproduce modulation of gut motility by bacteria in mice

C. West, A. Stanisz, Y. Mao, Kevin Champagne-Jorgensen, J. Bienenstock, W. Kunze

PLOS One, 2020

LRRTMs Organize Synapses through Differential Engagement of Neurexin and PTPσ

R. T. Roppongi, Shreya H. Dhume, N. Padmanabhan, Prabhisha Silwal, Nazmeena Zahra, B. Karimi, Claire Bomkamp, Chetan S. Patil, Kevin Champagne-Jorgensen, Rebecca E. Twilley, Peng Zhang, M. F. Jackson, Tabrez J. Siddiqui

Neuron, 2020

Prenatal low-dose penicillin results in long-term sex-specific changes to murine behaviour, immune regulation, and gut microbiota

Kevin Champagne-Jorgensen, M. F. Mian, S. Kay, Hila Hanani, O. Ziv, K. M. Neufeld, O. Koren, J. Bienenstock

Brain, Behavior, and Immunity, 2019

Antibiotics and the nervous system: More than just the microbes?

Kevin Champagne-Jorgensen, W. Kunze, P. Forsythe, J. Bienenstock, K. McVey Neufeld

Brain, Behavior, and Immunity, 2019

Oral selective serotonin reuptake inhibitors activate vagus nerve dependent gut-brain signalling

K. McVey Neufeld, J. Bienenstock, A. Bharwani, Kevin Champagne-Jorgensen, Y. Mao, C. West, Yunpeng Liu, M. Surette, W. Kunze, P. Forsythe

Scientific Reports, 2019

Low-density primary hippocampal neuron culture

R. T. Roppongi*, Kevin Champagne-Jorgensen*, Tabrez J. Siddiqui

Journal of Visualized Experiments : JoVE, 2017